Cortical visual prosthesis is contained from three components: 1) perceiving (video camera in eyewear) 2) transmitting/processing of video signal 3) brain-computer microelectron interface, stimulating visual cortex for shaping the image for the patient. Cortical visual prosthesis development present complicating requirements for brain-computer microelectron interface of cortical visual prosthesis. Nowadays common necessary requirements for successful and long-term implantation of functional cortical visual prosthesis are 1) biocompatible and spare for brain tissue implantation and no corrosion of microelectrodes in aggressive ion environment of brain liquor,
2) ability to implant microelectrodes via blood vessels plexus, potentially implantation “by parts”. 3) several sites of stimulation on one microelectrode for enhancing resolution of cortical prosthesis and diminishing the voltage high load to the brain tissue, 4) increase of quantity of electrodes of visual prosthesis, 5) working governing system development for microelectrodes development. In laboratory of neuroceybernetics we are developing microelectrode component of visual prosthesis taking into account aspiration to biocompatible and long-term implantation. Experiments are provided on rodents.